Scientists Spot Quadruple Helix DNA Working In Human CellsSubmitted by emalvini on Mon, 01/21/2013 - 12:46
Scientists Spot Quadruple Helix DNA Working In Human Cells
JAN 21, 2013 8:20 AM
Forget the humble double helix: scientists from Cambridge University have now spotted four-stranded strings of DNA working inside human cells.
The researchers have published a paper in Nature Chemistry which demonstrates the existence and function of quadruple helix human DNA. The researchers believe it might be related to cancer—and that understanding it could be key to treating the disease in the future. Prof Shankar Balasubramanian from Cambridge University explains to the BBC:
"The existence of these structures may be loaded when the cell has a certain genotype or a certain dysfunctional state. We need to prove that; but if that is the case, targeting them with synthetic molecules could be an interesting way of selectively targeting those cells that have this dysfunction."