Diabetes discovery: Protein pathway points to possible treatmentSubmitted by Bob-45 on Sun, 08/25/2013 - 19:50
Sun, 25 Aug 2013 13:30 CDT
Scientists have discovered that one of the most diabolical proteins implicated in diabetes not only kills insulin-producing cells through one mechanism, but also damages the cells it doesn't kill through a second, novel mechanism.
Reigning in this rogue protein, called TXNIP, could significantly control diabetes, a disease that affects nearly 9 percent of Americans and is rapidly becoming a major cause of death and disability worldwide.
The scientists, from the University of Alabama at Birmingham, identified several never-before-realized routes to target TXNIP with drugs. Their study appears today (Aug. 25) in the journal Nature Medicine.