The Daily Paul has been archived. Please see the continuation of the Daily Paul at Popular Liberty.com

Thank you for a great ride, and for 8 years of support!
31 votes

What I've learned from legal marijuana in my state.

Hey guys, this article "3 studies that show cannabis grows brain cells" set me on a writing tangent that I thought I should share.

Everything in this post has been learned by me in the past 3 months while the stores have been open. It takes a scientific outlook on the new things we are learning now that research can be legally conducted.

The endocannabinoid system is a system that acts upon literally every other system in your body. It regulates homeostasis of the bodily functions, in other words, it keeps every system in your body within certain parameters necessary for proper function. When cells get low on fuel, they send signals to the brain telling them the body needs an intake of food. The brain then releases a small amount of anandamide (endocannabinoid), and you literally give yourself the munchies. That happens every time you get hungry.

Phytocannabinoids, phyto meaning from the plant, endo meaning produced inside the body. There are scores of phytocannabinoids found in cannabis that act on your cannabinoid system with every one of them seeming to promote health and healing disease. Right now is one of the most exciting times for this research since the Bush/Clinton crime syndicate no longer has such a death grip on our laws. Families are uprooting their lives to move to Colorado and give this medicine to their children. This is criminal, no person should have to compromise anything in order to use a plant from the ground. Arguments to the contrary are an example of cognitive dissonance.

At the bottom of this post, I will give tips on preparing cannabinoids to be absorbed into the body to gain the benefits. EATING RAW CANNABIS WILL NOT GET YOU HIGH, AND WILL NOT ALLOW FOR MAXIMUM MEDICINAL BENEFITS. As most of the cannabinoids will simply pass through without absorption... It's a waste of weed.

Not much definitive research has been done because of CRIMINALS preventing free people from possessing an herb from God. This cult of statism has caused countless suffering and death by denial of a healing plant. As well as countless addictions and deaths occurring from unnecessary, harmful products produced by the pharmaceutical companies, enriching the Bush/Clinton syndicate.

Here's a look at some of the better known cannabinoids[1]:

THCA: tetrahydrocannbinolic acid. This is the most abundant phytocannabinoid found in cannabis. It is non-psychoactive. The molecule is identical to THC with the exception of a Carboxylic acid (COOH) group attached to it. It appears to hold great promise as an anti-oxidant and it's full medical benefits are still yet to be shown through scientific study. Once inside the body, there is almost zero conversion of THCA into THC, meaning the value of the medicine can be realized without the "high" that users experience.

THC: tetrahydrocannbinol. The famous psychoactive molecule of cannabis. Very little THC is found naturally in the cannabis plant. THC is produced when heat or time causes the COOH group to be knocked off of the THCA molecules. In smoked cannabis, the combustion converts a percentage of THCA into THC, causing the psychoactive effects. In eaten cannabis, cooking causes this. THC has been shown to have many positive effects in killing diseases. THC acts like anandamide as an agonist upon the CB1 receptor found throughout the central and peripheral nervous systems, giving it its psychoactive properties.

CBD: Cannabidiol. CBD is the second most abundant phytocannabinoid found in cannabis. It is the molecule that appears to hold the most medicinal properties found in cannabis. Though considered non-psychoactive, studies have shown CBD to have an antagonist role on the CB1 receptor, meaning it prevents or inhibits THC or anandamide from effecting the neurons carrying the CB1 receptor. Cannabis strains high in CBD such as Charlette's Web are in extreme demand due to the medical benefits of this molecule.

CBN: Cannabinol. CBN is not produced directly by the cannabis plant, but is produced when THC degrades over time. It is identical in structure to THC but with a butyl (4 carbon) chain instead of the pentyl (5 carbon) chain in THC. CBN is considered to be non-psychoactive but does act as an agonist on the CB2 receptor found throughout the peripheral nervous system possibly giving a "body high" some users experience. The CB2 receptor is not found in the central nervous system.

THCV: thetrahydrocannabivarin. Found more in sativa dominate strains, THCV is identical to THC and CBN except it has a propyl (3 carbon) chain instead of the butyl and pentyl chains found in CBN and THC respectively.

CBG: Cannabigerol. CBG is non-psychoactive. But it has been attributed to lowering intra-ocular pressure thereby reducing the harmful effects of glaucoma. Not many studies have focused on the effects of CBG.

CBC: Cannabichromene. Another non-psychoactive cannabinoid. Studies are being done to study anti-viral and anti-inflammatory effects of CBC.

Cannabinoid absorption into the body:

Cannabinoids are hydrophobic, meaning they are repelled by water and will not dissolve in water. It is very difficult to get high from cannabis tea, as the water prevents the cannabinoids from dissolving and absorbing into the bloodstream. However, cannabinoids will dissolve into fatty acids. Adding cream or milk to cannabis tea will greatly increase the absorption rate.

Because cannabinoids dissolve into fatty acids, and fatty acids are readily absorbed into the lymphatic system (the body loves fatty acids, and many of them bypass the bloodstream directly by going into the lymphatic system for faster utilization), this is the best way to make use of your medicine. Heat is a prerequisite to activating the psychoactive effects of cannabis, as raw cannabis will not get you high. If you would like to activate the psychoactive effects of cannabis, you must heat it before ingestion.

What I do is go to the store and get some cannabis oil concentrate (plant matter will work too, but it's harder to know the dose). I then get coconut oil for preparing the medicine (most oils or butters or creams will do, I prefer coconut oil). Most of the time, I prefer to activate the psychoactive effects for relaxation. If not, I'll heat up the coconut oil just enough to make it liquid (80 degrees) so the cannabinoids will dissolve, but I don't get high. To activate the psychoactive effects I'll put the equivalent in cannabis oil of about 100mg of THC into a shot glass full of coconut oil (the proper amount is extremely variable from person to person, know how much you personally can handle. Too much WILL NOT be enjoyable). I'll then place the shot glass in a partially filled pot of water (careful to keep the water out of the shot glass) and let simmer for about 20 minutes. This will decarboxylate the THCA into THC and activate the "high" users experience. After ~20 min of simmering, I will let the shot glass cool. Usually I'll speed up the cooling process by adding a bit of cold water to the simmering water. If you use purely cold water, you may end up cooling the glass too much causing it to crack, ruining the contents inside. Once cool, you have a fully prepared single dose of medicine, take the shot. I like this method because the simmering water guarantees the heat won't get over 212 degrees. Higher heats are not necessary. Plus it reminds me of the movie "Menace to Society." There are better ways to prepare it, but this one works for me and the main principles are communicated in the recipe.

This recipe is only for a single dose, but the ingredients can be extrapolated to make larger amounts. Just make sure you know how much you have in your final product. The stores label THC content, and this label is usually proportional to how much it will effect you. This single dose will last me the entire rest of the day if taken right after work and will be effective in treating my insomnia when I go to bed that night without further medication.

Key points:
-cannabinoids are hydrophobic and will not dissolve in water, nor be efficiently absorbed into the body without fatty acids.

-Raw cannabis will not be psychoactive, to activate the psychoactive effects, heat must be applied.

-liquid fatty acids dissolve the cannabinoids making the readily absorbable inside the gastrointestinal tract.

Pro-tip: Dark Chocolate contains anandamide, the endocannabinoid found in your body. Eating a bar of dark chocolate will add to the pleasurable effects of cannabis. Another neurotransmitter found in dark chocolate is oxytocin, afeel good drug. It also includes phenylalanine, which is an essential amino acid used in dopamine production.

And now you know how to properly prepare your medicine. Happy medication everyone! "The more you know..."

For more about the medical benefits of cannabis, YouTube videos of Dr. Bob Melamede and visit his University of Colorado at Colorado Springs page here: http://www.uccs.edu/~rmelamed/

Also be on the look out for the documentary "Run From the Cure II: Run 2 the Cure" which should be released later this year. Rick Simpson opened my eyes years ago to the corruption suppressing this medicine with his original documentary. See:
http://phoenixtears.ca

Works cited:

[1] http://www.cannlabs.com/the-science/cannabinoids/

PS: I must express my disappointment in the cannabis market in Colorado. The state has instituted such ridiculous taxes and are further trying to regulate it so much it pisses me off. My DP friends can understand this. Prices are 3 times higher than before the legal market. And higher than in other states' black markets. Direct sales taxes are 25%, but because the Feds won't allow the business to deduct legitimate business expenses, the effective tax is probably closer to 60-80%. People are still getting shot and killed in Colorado attempting to sell marijuana on the black market. See: http://www.startribune.com/politics/national/253860141.html. Further, the state is spending millions of dollars on TV ads informing people they can't drive high, as if this is some new phenomenon that wouldn't exist in a black market. These ads make cannabis users out to be a bunch of morons that can't perform the most basic tasks. My post above shatters the conventional image of a pot head in my opinion.

EDIT: To be clear, when I use the term "raw cannabis" I simply mean the plant material all by itself, unheated. If you take raw cannabis, and mix it with oil or some sort of fatty acid base, this is how you unlock the medical benefits. If you then heat that, you unlock the psychoactive effects. HEATING IS NOT NECESSARY FOR MEDICAL BENEFITS. And unheated, prepared cannabis is preferable for people that don't want the "high" associated with use.



Trending on the Web

Comment viewing options

Select your preferred way to display the comments and click "Save settings" to activate your changes.
deacon's picture

thats not personal experience

That is second hand experiences.
I have worked 12 -16 hours a day for over 25 years,and during this time,i smoked every day, and I still do.
I was a designer of pulper rotors,but this wasn't my job, I was just the operator of the pulpers. The rotors i designed put out double the amount of pulp in 24 hours,than the ones that were used and sold.
When the bobcat REPS came around to sell another bobcat,I was the one who helped design that machime,and that design is still used today.
In my garage I built the working platform for the DR mowers,this design was later stolen,and that machine is what you see nowadays...but it was mine !
i accumulated enough hours and points to retire early,so I had enough time in to retire at the age of 45
So you can say what you will about your friends,but do not include me,as it does not apply,nor will it ever.
D

Leave an indelible mark on all of those that you meet.
OH... have fun day :)
d

your friends are losers

and you're no better

Official Daily Paul BTC address: 16oZXSGAcDrSbZeBnSu84w5UWwbLtZsBms
Rand Paul 2016

Every time I here this I LOL!

Could it be your friends were idiots to start with and weed is just an excuse? Are you saying these friends were once successful in your eyes and now failing because of cannabis. Or your friends simply know something you don't. For example: How to live life their own way. Judging your friends for their "Laugh" really looks bad on you... As for their brain not being there? Have you considered that maybe what you are seeing in brilliance? Because there is often a fine line between Genius and Madness. Maybe they are also taking some prescriptions. These cholesterol drugs will rape your mind. I've been watching a family member deteriorate in front of my eyes because he has a Doctor he trusts prescribing a half chosen medications to a once healthy 38yo man which now struggles to do the most basic tasks.

I know

this is something people don't want to hear, ok, so I should keep my mouth shut, ok? I have nothing against MJ; I support the legalization of MJ; I have inhaled... more than once, but not for a very long time. I am only stating my observation...guess I need to do a scientific study or something.. my experience with scientific studies is that the results of the study are predicated on the premise the scientist started out with.

remember puma for life

anything can be abused, if they are over using water it can kill them. Cheeseburgers are addictive and will give you heart attacks if you take too many, just as aspirin if over taken will thin out your blood too much. The problem is not with the plant it is with people always needing more effect instead of enjoying the benefits of moderation.

Those who expect to reap the blessings of freedom must. like men, undergo the fatigue of supporting it.-Thomas Paine

The R3volution requires action, not observation!!!!

I agree...

I'm just saying that cannabis can affect the brain and in these two cases they are using it every day and they are stoned all day.

Does that couple

work out weekly?

Have a decent diet?

Have jobs?

Just curious.

If you don't know your rights, you don't have any.

Well...

one has a job the other is into music production and is mostly a hobby; diets? not particularly healthy..I guess I did not do a good job of describing their behaviors.

It just helps.

Reason why I ask those questions is because most Americans' diets aren't that great and it's a big reason why they feel like sheeit.

If you don't know your rights, you don't have any.

Correlation, not causation

.

"Tu ne cede malis, sed contra audentior ito."

Yep

that's also what the scientists and professionals say about autism and vaccines.

Though on the vaccine issue

I agree with you.

But my Dad says the same thing about how one of his friends from childhood wasn't successful, and he used cannabis, therefore cannabis makes you unsuccessful.

Use me as an example, i smoked all day every day last year and it was the most successful year in my life. I have a degree in engineering and work as a software developer. The only reason I've slowed down use this year is because of the outrageous prices. Also I'm trying to make the transition to eating or vaping, instead of smoking.

"Tu ne cede malis, sed contra audentior ito."

Welp, your two person case study is convincing to me.

I guess I was wrong guys, I guess I should retract everything in this post...

"Tu ne cede malis, sed contra audentior ito."

lol

you must hang out with stupid friends. Perhaps, the others, lawyers, doctors, business people who smoke on a regular basis that I know are effin morons. Is that what you're trying to say.

It's fucking neurogenetic

In the beginning of a change the patriot is a scarce man, and brave, and hated and scorned. When his cause succeeds, the timid join him, for then it costs nothing to be a patriot.

Do you smoke

MJ on a daily basis? For how long? Just wondering...

You state your professional friends smoke regularly..what does that mean? The people I referred to above smoke all day long for 40 years.

Everyday buddy

I'm with what ministry said. Yes, we smoke all the time. Go for a hike, smoke. Go snowboarding and smoke multiple times. Play soccer smoke before and after. Speaking of soccer, I had a head injury first game of the season; hence, smoke oil immediately to reduce the swelling- catch my drift.

I spill more weed in a day than most smoke in a lifetime.

In the beginning of a change the patriot is a scarce man, and brave, and hated and scorned. When his cause succeeds, the timid join him, for then it costs nothing to be a patriot.

i vape high thc cannabis oil every day and i'm smarter than you

explain that

Official Daily Paul BTC address: 16oZXSGAcDrSbZeBnSu84w5UWwbLtZsBms
Rand Paul 2016

I doubt

that you are smarter than me. What's your IQ?

420 what's yours?

i would have said 710 but you're not smart enough to figure that one out.

i know i'm smarter than you just because of your dumb collectivist comments.

“Reality is a crutch for people who can’t cope with drugs”
Lily Tomlin

Official Daily Paul BTC address: 16oZXSGAcDrSbZeBnSu84w5UWwbLtZsBms
Rand Paul 2016

I have no clue what you are talking about...

guess I better toke up before reading your comments.

I take a hit or two at night puma

and I am good. You are actually taking the overdone ridicule very well, please lay off puma peeps, he is being very rational. Teach with kindness. Puma I like to say if someone is lazy before they intake cannabis they will be lazy after they smoke it. I dont really believe it changes a persons intentions with life, but I can't say it won't if it is abused. Everything abused has consequences that are usually detrimental.

Those who expect to reap the blessings of freedom must. like men, undergo the fatigue of supporting it.-Thomas Paine

The R3volution requires action, not observation!!!!

I'm not implying it makes anyone lazy

these two guys actually do something...one more than the other; actually one sells real estate so he makes his own time. I am just commenting on brain functioning. To be honest, of course, alcohol does the same thing. I noticed that if I had a beer or two in the evening before going to work, I actually saw my brain working slower. Now, my work entailed using my brain, so if it wasn't functioning at prime I noticed it and I worked slower...but it still worked.

the problem is

you're comparing apples to oranges. Alcohol kills brain cells. Cannabis builds brain cells in the hippocampus- explain that one ;)

In the beginning of a change the patriot is a scarce man, and brave, and hated and scorned. When his cause succeeds, the timid join him, for then it costs nothing to be a patriot.

I have to comment on this

Everyone should be aware that the science on this is very mixed. There is actually a lot of scientific papers (not just random websites making stuff up) that have looked at cannabis physiologically. For example it seems that ingestion before age 18 can significantly reduce IQ (http://www.pnas.org/content/early/2012/08/22/1206820109?tab=...).

I'm not trying to argue or prove you wrong but I noticed that from all your sources, it all goes back to one scientific journal entry that isnt a conclusive study at all, (it just discusses potential of cannabis).

As a scientist in a rigorous field, I have found out how often "scientific facts" are very hard to find, and critical thinking must be applied when we read any article no matter the credentials. Nature isnt as simple as we would like her to be.

I guess what I'm suggesting is, dig into the literature. There are lots of scientific papers out there on this subject. Look into them. Don't just go to pro-pot websites. This isn't my area of expertise so i don't have the interest to research it but i would interested what someone found from a thorough scientific review of what we know.

that study was debunked under peer review

it was found to be more correlation related than causation.

Official Daily Paul BTC address: 16oZXSGAcDrSbZeBnSu84w5UWwbLtZsBms
Rand Paul 2016

Yeah, I agree.

I mean, it's an herb that grows in all climates all over the world. It defeats all other plant species in the plant equivilant of predator/prey of animals. And my god, it has male and female sexes. It is one of the most advanced plant species, if not the most advanced, in the world. All vertebrae have an endocannabinoid system, meaning fish and higher species. We evolved together, perhaps that's why it is so beneficial, and we likely evolved to benefit each other.

I think it is much more likely the stigma of using marijuana that harms young people's psychology than the marijuana itself.

"Tu ne cede malis, sed contra audentior ito."

That's a very valid point.

I didn't mean to imply that the first link was related to my post other than it inspired me to write the post.

My post is pretty much entirely unrelated, and the other links I offer lower in the post are good resources. Especially the YouTube videos of Dr. Bob Melamede.

"Tu ne cede malis, sed contra audentior ito."

That link can be confusing,

just click on the PDF picture next to "related content" to get the full article.

I believe you may be wrong on the raw cannabis

Yes. You are right. Raw cannabis will not get you high; however there is plenty of experiential observation with users who choose to ingest raw cannabis. I would like to continue this discussion further with you, as I too live in a legal state.

I was just eating young flowers a few days ago, and I really feel that it helps my poor dietary choices- specifically Colorado Microbrews- Modus Hoperandi. If I drink more than one, I can really feel the arthritis I've developed in numerous areas- especially my hands. The alcohol, sugars, and gluten are the culprits- I smoke non-stop, but really when I ingest the leaves raw, I feel alert without coffee jitters and as if my joints are well oiled.

I also ingest cannabis oil with coconut oil. I don't decarboxylate it anymore than it has been already. I extract my own oil and it sits on a double boiler with a quick blast from a propane torch. I keep it from getting too hot because then you'll degrade the sensitive terpene profile (next topic).

you're spot on with your cannabinoids. Also with your shot glass make sure its not sitting on the bottom of the pan, as it will be hotter than just the water bath. Maybe you use a thermometer (IDK), not criticizing just wanna help move some information with you :)

However, I went back to re-read and it seems like you contradict yourself with: EATING RAW CANNABIS WILL NOT GET YOU HIGH, AND WILL NOT ALLOW FOR MAXIMUM MEDICINAL BENEFITS

and: THCA: tetrahydrocannbinolic acid. This is the most abundant phytocannabinoid found in cannabis. It is non-psychoactive. The molecule is identical to THC with the exception of a Carboxylic acid (COOH) group attached to it. It appears to hold great promise as an anti-oxidant and it's full medical benefits are still yet to be shown through scientific study. Once inside the body, there is almost zero conversion of THCA into THC, meaning the value of the medicine can be realized without the "high" that users experience.

In the beginning of a change the patriot is a scarce man, and brave, and hated and scorned. When his cause succeeds, the timid join him, for then it costs nothing to be a patriot.

I love Modus Hoperandi too.

Sorry to hear it does that too you.

When I mention that raw cannabis will not yield maximum medical benefits, I'm referring to the fact that cannabinoids are hydrophobic, and if you just eat buds like popcorn, the water in your gut will prevent most of the absorption into the bloodstream. The cannabinoids must be somehow dissolved into a readily absorbable medium like fatty acids in order to gain maximum benefits. Though, I'm certain eating it raw will see some absorption, the vast majority of cannabinoids will not absorb into the bloodstream.

"Tu ne cede malis, sed contra audentior ito."