Found this short article about what depletes it....
What Depletes Glutathione?
cigarette smoke, pills
What depletes Glutathione (GSH) levels in our bodies can be put into two categories - internal and external factors.
Internal factors include the increasing need for Glutathione as an important part of various processes in our bodies, such as, food for our immune system, recycling of vitamin C, vitamin E and lipoic acid, repairing our DNA, and protecting our cells from oxidative stress to mention a few.
Many external factors is what depletes Glutathione the most.
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