Comment: Sure.

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In reply to comment: I'd be willing to bet that (see in situ)

Sure.

I never disputed that it would "stop" an average attacker, I'm disputing its lethality. Seriously, even a normal .44 won't do anything against Kevlar except hurt really badly - only a rifle or a specialized pistol round (7.62 Tokarev, for instance) could pierce it.

You target center body mass, not the head. Center body mass provides an abundance of vital organs to hit, and it's a much larger target. Headshots are hard anyway, and darn near impossible on a moving target. Average intruder breaks in and gets shot with a 9mm hollow point, average intruder will either die or end up in critical condition in the nearest hospital.

I've seen some of that show, and yes, a .22 out of a 20 inch barrel at point blank range to the back of the brain is indeed reliably lethal. A .22 out of a five-inch barrel at seven feet shooting at a moving torso, possibly through thick clothing?

I'm not saying that the .22 is useless - on the contrary, no prepper should be without one. I'm simply stating that larger calibers that can be easily handled by the shooter will be more reliably lethal than a .22LR ever stands a chance of being.