Tenth Amendment: “The powers not delegated to the United States by the Constitution, nor prohibited by it to the States, are reserved to the States respectively, or to the people.”
If the feds want to prohibit the use of certain drugs, pass a constitutional amendment which was done for alcohol prohibition (the 18th).
What part of the 10th don't the feds understand?
Solution: During Prohibition, juries refused to confict alcohol arrests - they "nullified" an unjust law. Juries may vote their conscience today also. See Fully Informed Jury Association www.fija.org No victim = NO CRIME!