Why not punish them instead? Doing otherwise is simply crazy.
We have to stop thinking of 'them' as everyone who is not us. Them is a collective of multiple subsets of us. A CFO of a major corporation might completely agree with us while only compromising (to CYA) on one tiny thing. Collectively, however, that compromise he made, along with the same from millions of others, constitutes the entirety of the problems we fight. It's simply as insane to target "them" as it is for the US to "fight terrorism". It's a battle that can't be won and never ends.
A much better method would be to pick one evil-doer and fight that entity. For example, debate it out among ourselves to identify the most evil company out there. It doesn't matter who is selected but they should have common negatives for all people and be easily taken down. Make this a public process that draws people in DURING THE DEBATE. Get that consensus and organize a mass boycott using those who learned of it during the debate.
You can't run a society by boycotting "gas and oil" but you certainly can by boycotting BP. Same goes with Monsanto but they're harder to take down because they don't sell directly to the people. So wait on tackling them until the process gains its strength.
In the boycott, we have to be clear that the people will not interact with said evil company in any way. We will not invest in them. The boycott will follow the CEO to his next company. We will swap out our investments from any fund that includes their stock. We will not interact with any company that interacts with them and so on. Create a public-sourced graph of their interactions with other companies and watch as those fall one-by-one. When the main company falls, we've succeeded. So move on.
Find the next company in an even more public debate. Let them know that whomever is in the running had better be scared. Let the fear of anticipation make them change their ways before we even get done picking the new 'winner'.
If this process became an ongoing one which consistently grew in popularity, our "top ten candidates" would quickly become mainstream news. At that point, we have all the power in the system. ...without punishing ourselves by going days without food, gas or income and definitely without firing a single shot.