Comment: Higher serum glucose levels

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Higher serum glucose levels

Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions.

CONCLUSIONS:

Higher fasting serum glucose levels in cognitively normal, nondiabetic adults may be associated with AD pathophysiology. Findings suggest that the risk imparted by higher serum glucose levels may be independent of APOEε4 status. This study raises additional questions about the role of the metabolic process in the predisposition to AD and supports the possibility of targeting these processes in presymptomatic AD trials.